rac-12-Selena-13,14-diazatricyclo[9.3.0.02,4]tetradeca-11,13-diene
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چکیده
منابع مشابه
Dmd058420 1314..1325
GSK1322322 (N-((R)-2-(cyclopentylmethyl)-3-(2-(5-fluoro-6-((S)-hexahydropyrazino[2,1-c][1,4]oxazin-8(1H)-yl)-2-methylpyrimidin-4-yl) hydrazinyl)-3-oxopropyl)-N-hydroxy-formamide) is an antibiotic in development by GlaxoSmithKline. In this study, we investigated the metabolism and disposition of [C]GSK1322322 in healthy humans and demonstrated the utility of the Entero-Test in a human radiolabel...
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Loss of neurons that express the neuropeptide hypocretin (Hcrt) has been implicated in narcolepsy, a debilitating disorder characterized by excessive daytime sleepiness and cataplexy. Cell replacement therapy, using Hcrt-expressing neurons generated in vitro, is a potentially useful therapeutic approach, but factors sufficient to specify Hcrt neurons are unknown. Using zebrafish as a highthroug...
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The genetic control of mammalian epithelial polarity and dynamics can be studied in vivo at cellular resolution during morphogenesis of the mouse neural tube. Themouse neural plate is a simple epithelium that is transformed into a columnar pseudostratified tube over the course of ∼24 h. Apical F-actin is known to be important for neural tube closure, but the precise roles of actin dynamics in t...
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An underlying assumption of the above parametric approach is that the process is a = Gaussian field, i.e., its statistical characteristics, including its roughness parameter (or its reciprocal, the smoothness ) ), are the same at each point in the image. The FWHM of the process should be constant in all directions and across all voxels in the image. While these assumptions are reasonable for fu...
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The historical sediment record of Lake Sonachi (Kenya) was used to study the influence of lake depth and mixing regime on patterns of sedimentation in a small, fluctuating tropical soda lake. Lake Sonachi last desiccated completely in the early nineteenth century and has fluctuated between 3and 18-m lake depth over the past 115 yr. A freeze-core of offshore sediments describes recent lake histo...
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ژورنال
عنوان ژورنال: IUCrData
سال: 2020
ISSN: 2414-3146
DOI: 10.1107/s2414314620010810